भूतानाम् for all beings, आगतिम् transient happenings, अनियताम् एव as it is unstable, जानासि you know, तस्मात् therefore, पण्डितेन by the wise, इह here, लौकिकम् worldly, शुभम् auspicious, कर्तव्यं हि is to be done.

'You are aware of the uncertain and transient happenings in the lives of living beings. Therefore, a wise lady should do auspicious work in this world.