Valmiki Ramayana Ayodhya Kanda Sarga 22 Shloka 23

उग्रतपसः practising severe austerities, ऋषयोऽपि rishis also, दैवेन by destiny, अभिप्रपीडिताः tormented, तीव्रान् severe, नियमान् observances, उत्सृज्य setting aside, काममन्युभिः with anger and passion, भ्रश्यन्ते are fallen.

Even rishis with severe austerities are tormented by destiny and are swerved from their observances because of anger and passion.